Nobel prize for elucidating the molecular structure of dna
After Miescher’s isolation of the curious substance, other researchers then took up the baton and got to grips with characterising its chemical structure.Albrecht Kossel, a biochemist from Rostock in Germany determined that “nuclein” was composed of both protein and non-protein portions.
By 1900, Mendel’s principles had been independently verified and then rediscovered by at least four other scientists, and approximately 10 years previously the Dutch botanist Hugo de Vries proposed that the inheritance of traits might be mediated by discrete elements or particles, termed “pangenes”. The structures that we now know as chromosomes were independently observed by several German and Swiss scientists from the mid-1800s onwards.His crowning achievement, for which he received the Nobel Prize in Physiology or Medicine in 1910, was the eventual isolation of the five so-called nucleobases from the non-protein portion: adenine, cytosine, guanine, thymine and uracil.The next major milestone was the elucidation of the chemical structure of these building blocks of DNA.“It’s exciting and interesting to see what it takes to get an award like that. In 1866, a German-speaking monk named Gregor Johann Mendel from today’s Czech Republic publishes a scientific treatise concerning the inheritance of traits in peas……five years later, a Swiss researcher called Friedrich Miescher isolates a mysterious phosphate-rich substance from the nuclei of white blood cells, which he christens “nuclein”.